Drug Profile
Sotevtamab - Alethia BioTherapeutics/International Biotechnology Center Generium
Alternative Names: 16B5; AB-16B5; AB-sCLU mAB; Anti-clusterin monoclonal antibody - Alethia BiotherapeuticsLatest Information Update: 14 Mar 2024
Price :
$50
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At a glance
- Originator National Research Council Biotechnology Research Institute
- Developer Alethia BioTherapeutics
- Class Antineoplastics; Immunotherapies; Monoclonal antibodies
- Mechanism of Action Clusterin inhibitors
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Phase II Colorectal cancer; Non-small cell lung cancer
- No development reported Solid tumours
Most Recent Events
- 15 Feb 2024 Phase-II clinical trials in Colorectal cancer (Combination therapy, Metastatic disease, Neoadjuvant therapy, Late-stage disease) in Canada (IV) (NCT06225843)
- 26 Jan 2024 Alethia Biotherapeutics plans a phase II trial for Colorectal Cancer (Combination therapy, Late-stage disease, Metastatic disease, Neoadjuvant therapy) in Canada (IV, Infusion) in February 2024 (NCT06225843)
- 31 Dec 2023 Alethia Biotherapeutics completes a phase II trial in Non-small cell lung cancer (Metastatic disease, Late-stage disease, Combination therapy, Second-line therapy or greater) in Canada and the US (IV, Infusion) (NCT04364620)