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ARX 788

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Drug Profile

ARX 788

Alternative Names: Antibody-drug conjugate - Ambrx/Zhejiang Medicine; ARX-788; NCB-001

Latest Information Update: 13 Mar 2024

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At a glance

  • Originator Ambrx
  • Developer Ambrx; NovoCodex Biopharmaceuticals
  • Class Antineoplastics; Drug conjugates; Immunoconjugates; Immunotoxins; Monoclonal antibodies; Small molecules
  • Mechanism of Action Tubulin inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Gastric cancer
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase II/III HER2 positive breast cancer
  • Phase I Gastric cancer
  • Suspended Breast cancer; Solid tumours

Most Recent Events

  • 07 Mar 2024 Ambrx has been acquired by Johnson & Johnson
  • 25 Jan 2024 Ambryx plans a phase II trial for Breast cancer (Late-stage disease, Inoperable/Unresectable, Second-line therapy or greater, Metastatic disease) in the US (IV) (NCT06224673)
  • 05 Dec 2023 Efficacy and adverse events data from a phase I trial in Solid tumours cancer presented at the 46th Annual San Antonio Breast Cancer Symposium (SABCS-2023)
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