GDC 0994

Drug Profile

GDC 0994

Alternative Names: GD0 994; GDC-0994; RG-7842

Latest Information Update: 25 May 2017

Price : $50

At a glance

  • Originator Array BioPharma
  • Developer Genentech
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Extracellular signal-regulated MAP kinase inhibitors; Mitogen activated protein kinase 3 inhibitors; Mitogen-activated protein kinase 1 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Solid tumours

Most Recent Events

  • 01 Apr 2017 Efficacy and adverse events data from a phase I trial in Solid tumours presented at 108th Annual Meeting of the American Association for Cancer Research (AACR-2017)
  • 05 Dec 2016 Genentech completes a phase I trial in Solid tumours (Combination therapy, Late-stage disease, Metastatic disease, Second-line therapy or greater) in USA (PO) (NCT02457793)
  • 29 Nov 2016 Pharmacodynamics data from a preclinical trial in Solid tumours presented at the 28th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics (EORTC-NCI-AACR-2016)
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