GR MD 02

Drug Profile

GR MD 02

Alternative Names: Galactoarabino-rhamnogalaturonate

Latest Information Update: 19 Dec 2017

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At a glance

  • Originator Galectin Therapeutics
  • Developer Galectin Therapeutics; Providence Cancer Center; Providence Health & Services
  • Class Antifibrotics; Antineoplastics; Antipsoriatics; Carbohydrates; Hepatoprotectants; Polysaccharides; Skin disorder therapies
  • Mechanism of Action Galectin 3 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase II Atopic dermatitis; Hepatic fibrosis; Liver cirrhosis; Plaque psoriasis
  • Phase I Head and neck cancer; Lung cancer; Malignant melanoma; Orofacial cancer
  • Preclinical Breast cancer; Diabetic nephropathies; Fibrosis; Prostate cancer; Pulmonary fibrosis; Renal fibrosis
  • Discontinued Non-alcoholic steatohepatitis

Most Recent Events

  • 14 Dec 2017 GR MD 02 is available for licensing as of 14 Dec 2017.
  • 14 Dec 2017 Efficacy data from the phase IIb NASH-CX trial in Non-alcoholic steatohepatitis released by Galectin Therapeutics
  • 05 Dec 2017 Efficacy data from a phase II trial in Non-alcoholic steatohepatitis released by Galectin Therapeutics
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