Drug Profile


Alternative Names: 3-bromopyruvate; 3-bromopyruvic acid; 3-BrPA; PSL-001

Latest Information Update: 16 Jul 2016

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At a glance

  • Originator Johns Hopkins University
  • Developer PreScience Labs
  • Class Antineoplastics; Keto acids; Pyruvates; Small molecules
  • Mechanism of Action Alkylating agents; MASP2 protein inhibitors; Pyruvate dehydrogenase complex inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • No development reported Cancer

Most Recent Events

  • 16 Jul 2016 No recent reports of development identified for preclinical development in Cancer in USA (Intra-arterial)
  • 24 Jul 2013 The US FDA approves IND application for bromopyruvate in Liver cancer
  • 01 Jan 2010 Preclinical trials in Cancer in USA (Intra-arterial)
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