Rovalpituzumab tesirine

Drug Profile

Rovalpituzumab tesirine

Alternative Names: Rova-T; SC16LD6.5

Latest Information Update: 25 Mar 2017

Price : $50

At a glance

  • Originator Stemcentrx
  • Class Antineoplastics; Drug conjugates; Immunoconjugates; Monoclonal antibodies
  • Mechanism of Action DLL3 protein inhibitors; DNA modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Small cell lung cancer
  • On Fast track

    Fast track status is assigned by the US FDA so therapies with the potential to address unmet needs can move faster through development.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Small cell lung cancer
  • Phase I/II Solid tumours

Most Recent Events

  • 02 Mar 2017 AbbVie plans a phase III trial for Small cell lung cancer (Metastatic-disease, Late-stage disease, Second-line therapy or greater) (NCT03061812)
  • 07 Feb 2017 Phase-III clinical trials in Small cell lung cancer (Second-line therapy or greater, Metastatic disease) in USA (IV) (NCT03033511)
  • 25 Jan 2017 AbbVie plans the phase III MERU trial for Small cell lung cancer (Late stage disease, Maintenance therapy) in USA (IV) (NCT03033511)
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