RXDX 105

Drug Profile

RXDX 105

Alternative Names: AC 013773; CEP-32496; RXDX-105

Latest Information Update: 15 Jun 2017

$50 / €47 *
* $ price applies to USA, Canada and Latin America. € price applies to the rest of the world. Final gross prices may vary according to local VAT.

At a glance

  • Originator Ambit Biosciences Corporation; Cephalon
  • Developer Ignyta
  • Class Antineoplastics; Isoxazoles; Phenyl ethers; Phenylurea compounds; Quinazolines; Small molecules
  • Mechanism of Action Epidermal growth factor receptor antagonists; Proto oncogene protein b raf inhibitors; Proto oncogene protein c ret inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Solid tumours

Most Recent Events

  • 14 Mar 2017 Ignyta has patent protection for RXDX 105 in USA
  • 16 Feb 2017 Ignyta initiates an expanded access to RXDX 105 for Cancer in USA before February 2017 (NCT03052569)
  • 01 Dec 2016 Interim efficacy and adverse events data from phase Ib part of the phase I/Ib trial in Solid tumours presented at the 28th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics (AACR-NCI-EORTC-2016)
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