OMS 721

Drug Profile

OMS 721

Alternative Names: anti-MASP-2 monoclonal antibody; MASP-2 therapeutic; OMS-721

Latest Information Update: 07 Aug 2017

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At a glance

  • Originator Omeros Corporation
  • Class Anti-inflammatories; Antithrombotics; Monoclonal antibodies
  • Mechanism of Action MASP2 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Thrombotic microangiopathies; IgA nephropathy
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Haemolytic uraemic syndrome
  • Phase II Glomerulonephritis; IgA nephropathy; Lupus nephritis; Membranous glomerulonephritis; Thrombotic microangiopathies
  • Preclinical Stroke; Wet age-related macular degeneration

Most Recent Events

  • 04 Aug 2017 OMS 721 receives Orphan Drug status for IgA nephropathy in USA
  • 13 Jun 2017 OMS 721 receives Breakthrough Therapy status for IgA nephropathy in USA
  • 17 May 2017 Interim efficacy data from phase II trial in Glomerulonephritis released by Omeros Corporation
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