OMS 721

Drug Profile

OMS 721

Alternative Names: anti-MASP-2 monoclonal antibody; MASP-2 therapeutic; OMS-721

Latest Information Update: 03 Mar 2017

Price : $50

At a glance

  • Originator Omeros Corporation
  • Class Anti-inflammatories; Antithrombotics; Monoclonal antibodies
  • Mechanism of Action MASP2 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Thrombotic microangiopathies
  • On Fast track

    Fast track status is assigned by the US FDA so therapies with the potential to address unmet needs can move faster through development.

    Haemolytic uraemic syndrome
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Haemolytic uraemic syndrome
  • Phase II Glomerulonephritis; IgA nephropathy; Lupus nephritis; Membranous glomerulonephritis; Thrombotic microangiopathies
  • Preclinical Stroke; Wet age-related macular degeneration

Most Recent Events

  • 01 Mar 2017 Omeros initiates compassionate use programme for OMS 721 in USA
  • 01 Mar 2017 Additional adverse events data from a phase II trial in Thrombotic microangiopathies released by Omeros
  • 06 Dec 2016 Efficacy data from a compassionate use programme in Thrombotic microangiopathies released by Omeros
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