Nitric oxide inhalation - AIT

Drug Profile

Nitric oxide inhalation - AIT

Alternative Names: AIT-CF; Nitric oxide inhaled; NOxAST; NOxBR; NOxCF; NOxCureBR; NOxCureCF; NOxPN

Latest Information Update: 21 Mar 2017

Price : $50

At a glance

  • Originator University of British Columbia
  • Developer AIT; Schneider Childrens Medical Center of Israel; University of British Columbia
  • Class Antiacnes; Antiandrogens; Antibacterials; Antihypertensives; Antivirals; Free radicals; Nitrogen oxides; Non-opioid analgesics; Small molecules; Vasodilators
  • Mechanism of Action Guanylate cyclase stimulants; Reactive oxygen species modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Cystic fibrosis
  • On Fast track

    Fast track status is assigned by the US FDA so therapies with the potential to address unmet needs can move faster through development.

  • New Molecular Entity No

Highest Development Phases

  • Phase III Respiratory syncytial virus infections
  • Phase II Cystic fibrosis
  • Phase I Pneumonia; Respiratory tract infections
  • Research Asthma

Most Recent Events

  • 05 Mar 2017 Phase-III clinical trials in Respiratory syncytial virus infections (In infants) in Israel (Inhalation) (NCT03053388)
  • 20 Feb 2017 AIT plans a phase III trial for Respiratory syncytial virus infections (In infants) (NCT03053388)
  • 27 Apr 2016 AIT completes a phase II clinical trial in Respiratory syncytial virus infections (In infants) in Israel (Inhalation) (NCT01768884)
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