Nitric oxide inhalation - AIT

Drug Profile

Nitric oxide inhalation - AIT

Alternative Names: AIT-CF; AIT-COPD; AIT-NTM; AIT-NV; AIT-RSV; AIT-WH; Nitric oxide inhaled; NOxAST; NOxBR; NOxCF; NOxCureBR; NOxCureCF; NOxPN

Latest Information Update: 04 Nov 2017

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At a glance

  • Originator University of British Columbia
  • Developer AIT; Schneider Childrens Medical Center of Israel; University of British Columbia
  • Class Anti-inflammatories; Antiacnes; Antiandrogens; Antibacterials; Antifungals; Antihypertensives; Antivirals; Free radicals; Macromolecular substances; Nitrogen oxides; Non-opioid analgesics; Small molecules; Vasodilators
  • Mechanism of Action Guanylate cyclase stimulants; Reactive oxygen species modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Mycobacterial infections; Cystic fibrosis
  • New Molecular Entity No

Highest Development Phases

  • Phase III Respiratory syncytial virus infections
  • Phase II Chronic obstructive pulmonary disease; Cystic fibrosis; Diabetic foot ulcer; Mycobacterial infections; Stroke
  • No development reported Respiratory tract infections
  • Discontinued Asthma; Pneumonia

Most Recent Events

  • 04 Nov 2017 No recent reports of development identified for phase-I development in Respiratory-tract-infections(In volunteers) in Canada (Inhalation)
  • 03 Oct 2017 Nitric oxide inhalation receives Orphan Drug status for Mycobacterial infections in USA
  • 13 Sep 2017 Efficacy data from a compassionate use trial in Cystic fibrosis released by AIT Therapeutics
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