Research programme: nitric oxide therapeutics topical - Novan Therapeutics

Drug Profile

Research programme: nitric oxide therapeutics topical - Novan Therapeutics

Alternative Names: CR 2005; CR 2016; Nitric Oxide Advanced Healing technology - Novan Therapeutics; NOAH technology - Novan Therapeutics; NVN 4428; NVN-4000; SB 414

Latest Information Update: 05 May 2017

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At a glance

  • Originator Novan Inc
  • Class Anti-inflammatories; Antiacnes; Antiandrogens; Antibacterials; Antifungals; Antihypertensives; Antivirals; Free radicals; Macromolecular substances; Nitrogen oxides; Non-opioid analgesics; Small molecules; Vasodilators
  • Mechanism of Action Angiogenesis inducing agents; Nitric oxide stimulants; Reactive oxygen species modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Preclinical Atopic dermatitis; Psoriasis
  • Discontinued Burns; Onychomycosis; Staphylococcal infections; Wound infections; Wounds

Most Recent Events

  • 27 Apr 2017 Pharmacodynamics data from a preclinical study in Atopic dermatitis released by Novan
  • 20 Mar 2017 Novan announces intention to submit an IND application for SB 414 for Psoriasis
  • 22 Nov 2016 Discontinued - Preclinical for Wounds in USA (Topical)
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