Research programme: antibody targeted amanitin conjugates - Heidelberg Pharma Research

Drug Profile

Research programme: antibody targeted amanitin conjugates - Heidelberg Pharma Research

Alternative Names: anti-CD19-amanitin conjugate; anti-CD269-amanitin conjugate; ATACs - Heidelberg Pharma Research/Roche; BCMA-amanitin conjugate; CD 19 - ATAC; HDP-101; HDP-101-ATAC

Latest Information Update: 13 Oct 2017

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At a glance

  • Originator Heidelberg Pharma
  • Developer Heidelberg Pharma Research; WILEX AG
  • Class Drug conjugates; Immunotoxins
  • Mechanism of Action DNA-directed RNA polymerase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Preclinical Haematological malignancies; Multiple myeloma; Solid tumours

Most Recent Events

  • 09 Oct 2017 Heidelberg Pharma is now called Heidelberg Pharma Research
  • 20 Sep 2017 Heidelberg Pharma plans a phase I trial for Multiple myeloma by the end of 2018
  • 05 Apr 2017 Pharmacokinetics and pharmacodynamics data from a preclinical study in Solid tumours presented at the 108th Annual Meeting of the American Association for Cancer Research (AACR-2017)
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