Drug Profile


Alternative Names: AFN 1720; AFN-1252-prodrug; Debio 1450; Debio-1452-prodrug

Latest Information Update: 12 Jan 2017

Price : $50

At a glance

  • Originator Affinium Pharmaceuticals
  • Developer Debiopharm Group
  • Class Anti-infectives; Benzofurans; Naphthyridines; Small molecules
  • Mechanism of Action Enoyl-ACP reductase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Osteomyelitis
  • New Molecular Entity No

Highest Development Phases

  • Phase II Skin and soft tissue infections
  • Phase I Bone and joint infections; Staphylococcal infections

Most Recent Events

  • 10 Jan 2017 Topline efficacy data from phase II trial in Skin and soft tissue infections released by Debiopharm Group
  • 25 Oct 2016 Debio 1450 receives Orphan Drug status for Osteomyelitis in European Union
  • 25 Oct 2016 Debiopharm completes a phase II trial in Acute bacterial skin and skin structure infections in USA (NCT02426918)
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