Drug Profile


Alternative Names: AFN 1720; AFN-1252-prodrug; Debio 1450; Debio-1452-prodrug

Latest Information Update: 06 Oct 2017

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At a glance

  • Originator Affinium Pharmaceuticals
  • Developer Debiopharm Group
  • Class Anti-infectives; Benzofurans; Naphthyridines; Small molecules
  • Mechanism of Action Enoyl-ACP reductase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Osteomyelitis
  • New Molecular Entity No

Highest Development Phases

  • Phase II Skin and soft tissue infections
  • Phase I Bone and joint infections
  • No development reported Staphylococcal infections

Most Recent Events

  • 06 Oct 2017 Debiopharm completes a phase I drug-drug interaction trial in Healthy volunteers in United Kingdom (PO) (NCT03209648)
  • 28 Jul 2017 Chemical structure information added
  • 07 Jul 2017 No development reported - Phase-I for Staphylococcal infections (In volunteers) in USA (PO; Tablet, Liquid, Suspension)
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