Olumacostat glasaretil

Drug Profile

Olumacostat glasaretil

Alternative Names: DRM 01; DRM-01B; VAL-001

Latest Information Update: 12 Oct 2017

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At a glance

  • Originator QLT
  • Developer Dermira
  • Class Antiacnes; Furans; Small molecules
  • Mechanism of Action Acetyl-CoA carboxylase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Acne vulgaris

Most Recent Events

  • 05 Oct 2017 Dermira completes enrolment in its two phase III trials (CLAREOS-1 and CLAREOS-2) for Acne vulgaris (In Children, in adolescents, in adults, in elderly) in USA, Canada and Australia (Topical)
  • 21 Mar 2017 Dermira initiate a long term phase III safety trial in Acne vulgaris in USA, Australia and Canada (NCT03127956)
  • 03 Mar 2017 Efficacy data from a phase IIb trial in Acne vulgaris presented at 75th Annual Meeting of the American Academy of Dermatology (AAD)
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