ME 401

Drug Profile

ME 401

Alternative Names: Kinase program - MEI Pharma; ME401; PWT-143

Latest Information Update: 18 Sep 2017

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At a glance

  • Originator Pathway Therapeutics
  • Developer MEI Pharma
  • Class Antineoplastics
  • Mechanism of Action Phosphatidylinositol 3 kinase delta inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Chronic lymphocytic leukaemia; Follicular lymphoma; Haematological malignancies

Most Recent Events

  • 31 May 2017 Safety data from a phase Ib trial in Chronic lymphocytic leukaemia and Follicular lymphoma released by MEI Pharma
  • 24 Feb 2017 MEI Pharma completes a phase I trial in Haematological malignancies in the UK (NCT02521389)
  • 01 Sep 2016 Phase-I clinical trials in Chronic lymphocytic leukaemia (Second-line therapy or greater) in USA (unspecified route) (NCT02914938)
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