PLX 7486Alternative Names: PLX-7486; PLX7486-TsOH
Latest Information Update: 18 Apr 2016
At a glance
- Originator Plexxikon
- Class Antineoplastics; Small molecules
- Mechanism of Action Fms-like tyrosine kinase 3 inhibitors; TrkA receptor antagonists; TrkB receptor antagonists; TrkC receptor antagonists
Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
On Fast track
Fast track status is assigned by the US FDA so therapies with the potential to address unmet needs can move faster through development.
- New Molecular Entity Yes
Highest Development Phases
- Phase I Pancreatic cancer; Solid tumours