Drug Profile


Alternative Names: Dual SYK/JAK inhibitor - Portola; PRT 2070; PRT-062070; RVT-502; RVT-502 - Dermavant Sciences

Latest Information Update: 31 Jan 2017

Price : $50

At a glance

  • Originator Portola Pharmaceuticals
  • Developer Dermavant Sciences; NicOx; Portola Pharmaceuticals
  • Class Anti-inflammatories; Antiallergics; Antineoplastics; Antirheumatics; Eye disorder therapies; Small molecules
  • Mechanism of Action Janus kinase inhibitors; Syk kinase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Chronic lymphocytic leukaemia; Non-Hodgkin's lymphoma
  • Phase I Skin disorders
  • No development reported Allergic rhinitis; Eye disorders

Most Recent Events

  • 31 Jan 2017 Phase-I clinical trials in Skin disorders in Switzerland (Topical) before January 2017 (Roivant Sciences pipeline, January 2017)
  • 21 Dec 2016 Dermavant Sciences in-licenses topical formulations of cerdulatinib from Portola Pharmaceuticals for skin disorders
  • 21 Dec 2016 Preclinical trials in Skin disorders in Switzerland (Topical)
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