Drug Profile


Alternative Names: SGN-LIV1A

Latest Information Update: 16 Oct 2017

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At a glance

  • Originator Seattle Genetics
  • Class Antineoplastics; Auristatins; Drug conjugates; Immunoconjugates; Monoclonal antibodies
  • Mechanism of Action Apoptosis stimulants; Mitosis inhibitors; Tubulin inhibitors; Tubulin polymerisation inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Phase I Breast cancer

Most Recent Events

  • 11 Oct 2017 Seattle Genetics signs a collaboration with Merck to evaluate SGN-LIV1A in combination with pembrolizumab
  • 11 Oct 2017 Seattle Genetics intends to evaluate SGN LIV1A as neoadjuvant treatment in the phase II I-SPY 2 trial for Breast Cancer
  • 11 Oct 2017 Seattle Genetics plans a phase Ib/II trial for Breast cancer in combination with pembrolizumab
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