CB 839

Drug Profile

CB 839

Alternative Names: CB-839

Latest Information Update: 08 Feb 2017

Price : $50

At a glance

  • Originator Calithera Biosciences
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Glutaminase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • On Fast track

    Fast track status is assigned by the US FDA so therapies with the potential to address unmet needs can move faster through development.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Renal cell carcinoma
  • Phase I/II Malignant melanoma; Non-small cell lung cancer
  • Phase I Haematological malignancies; Leukaemia; Solid tumours

Most Recent Events

  • 21 Dec 2016 Phase-II clinical trials in Renal cell carcinoma (Combination therapy, Late-stage disease, Metastatic disease, Second-line therapy or greater) in USA (PO)
  • 06 Dec 2016 Adverse events and efficacy data from a phase I trial in Solid tumours released by Calithera Biosciences
  • 29 Nov 2016 Updated efficacy and adverse events data from a phase I trial in Solid tumours released by Calithera Biosciences
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