CB 839

Drug Profile

CB 839

Alternative Names: CB839

Latest Information Update: 09 Jun 2017

Price : $50

At a glance

  • Originator Calithera Biosciences
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Glutaminase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Malignant melanoma; Non-small cell lung cancer; Renal cell carcinoma
  • Phase I Haematological malignancies; Leukaemia; Solid tumours

Most Recent Events

  • 07 Jun 2017 CB 839 receives Fast Track designation for Renal cell carcinoma [PO,Capsule] (Combination therapy, Late-stage disease, Metastatic disease, Second-line therapy or greater) in USA
  • 25 May 2017 Calithera Biosciences plans a phase II trial for Renal cell carcinoma (Metastatic disease, Late-stage disease, Combination therapy) (NCT03163667)
  • 10 May 2017 Bristol-Myers Squibb and Calithera Biosciences expand an existing clinical collaboration for Non-small cell lung cancer and Melanoma (Combination therapy)
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