ALT 803

Drug Profile

ALT 803

Alternative Names: ALT-803; IL-15N72D:IL-15RαSu/Fc fusion protein complex

Latest Information Update: 17 Jul 2017

Price : $50

At a glance

  • Originator Altor BioScience Corporation; NantKwest
  • Developer Altor BioScience Corporation; Masonic Cancer Center; NantKwest; University of Minnesota; University of South Carolina
  • Class Antineoplastics; Interleukins; Recombinant fusion proteins
  • Mechanism of Action Interleukin-15 receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II/III Bladder cancer
  • Phase II Acute myeloid leukaemia; Merkel cell carcinoma
  • Phase I/II Haematological malignancies; Multiple myeloma; Non-Hodgkin's lymphoma; Non-small cell lung cancer; Pancreatic cancer
  • Phase I HIV infections; Malignant melanoma
  • Preclinical Bacterial infections

Most Recent Events

  • 29 Jun 2017 NantCell plans the phase Ib/II QUILT-3.051 trial for Ovarian cancer (Combination therapy, Second-line therapy or greater) in September 2017 (NCT03197584)
  • 20 Jun 2017 NantCell plans the phase Ib/II QUILT-3.048 trial for Urogenital cancer (Second-line therapy or greater, Combination therapy) (NCT03197571)
  • 02 Jun 2017 NantCell plans the phase Ib/II QUILT-3.044 trial for Non-small cell lung cancer (Combination therapy, Second-line therapy or greater) (NCT03169738)
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