ALT 803

Drug Profile

ALT 803

Alternative Names: ALT-803; IL-15N72D:IL-15RαSu/Fc fusion protein complex

Latest Information Update: 14 Feb 2017

Price : $50

At a glance

  • Originator Altor BioScience Corporation; NantKwest
  • Developer Altor BioScience Corporation; University of Minnesota; University of South Carolina
  • Class Antineoplastics; Interleukins; Recombinant fusion proteins
  • Mechanism of Action Immunostimulants; Interleukin-15 receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Bladder cancer; Haematological malignancies; Multiple myeloma; Non-Hodgkin's lymphoma; Non-small cell lung cancer; Pancreatic cancer
  • Phase I HIV infections; Malignant melanoma
  • Preclinical Bacterial infections
  • Phase Unknown Acute myeloid leukaemia; Myelodysplastic syndromes

Most Recent Events

  • 22 Feb 2017 Masonic Cancer Center plans a phase I QUILT-2.021 trial for Ovarian cancer, Fallopian tube and primary peritoneal cancer (Late-stage disease, Second-line therapy or greater) in USA (NCT03054909)
  • 13 Feb 2017 Masonic Cancer Center, University of Minnesota plans a phase II trial for Acute myeloid leukaemia in USA (NCT03050216)
  • 17 Jan 2017 Altor Bioscience Corporation plans the phase II/III QUILT-3.032 trial for Bladder cancer (Combination therapy) in USA (Intravesicular) (NCT03022825)
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