ALT 803

Drug Profile

ALT 803

Alternative Names: ALT-803; IL-15N72D:IL-15RαSu/Fc fusion protein complex

Latest Information Update: 05 May 2017

Price : $50

At a glance

  • Originator Altor BioScience Corporation; NantKwest
  • Developer Altor BioScience Corporation; University of Minnesota; University of South Carolina
  • Class Antineoplastics; Interleukins; Recombinant fusion proteins
  • Mechanism of Action Immunostimulants; Interleukin-15 receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II/III Bladder cancer
  • Phase I/II Haematological malignancies; Multiple myeloma; Non-Hodgkin's lymphoma; Non-small cell lung cancer; Pancreatic cancer
  • Phase I HIV infections; Malignant melanoma
  • Preclinical Bacterial infections

Most Recent Events

  • 02 May 2017 Phase-II/III clinical trials in Bladder cancer (Combination therapy) in USA (Intravesicular)
  • 02 May 2017 ALT 803 receives Fast Track designation for Bladder cancer [Intravesicular,Liquid] (Combination therapy) in USA
  • 27 Apr 2017 NantCell plans a phase I/II trial for Solid tumours (Combination therapy, Metastatic disease, Late-stage disease, Second-line therapy or greater) (NCT03127098)
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