PEG ilodecakin

Drug Profile

PEG ilodecakin

Alternative Names: AM 0010; PEG-ilodecakin; PEG-rHuIL-10; Pegilodecakin; PEGylated Human IL-10; PEGylated Interleukin-10; PEGylated recombinant human Interleukin-10

Latest Information Update: 18 Oct 2017

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At a glance

  • Originator Merck & Co
  • Developer ARMO Biosciences
  • Class Anti-inflammatories; Antineoplastics; Immunotherapies; Interleukins; Polyethylene glycols
  • Mechanism of Action Interleukin-10 replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Pancreatic cancer
  • New Molecular Entity No

Highest Development Phases

  • Phase III Pancreatic cancer
  • Phase I Breast cancer; Colorectal cancer; Malignant melanoma; Non-small cell lung cancer; Ovarian cancer; Prostate cancer; Renal cell carcinoma
  • Preclinical Fibrosis; Hypercholesterolaemia; Inflammatory bowel diseases

Most Recent Events

  • 08 Sep 2017 Updated interim efficacy and adverse events data from a phase I trial in Non-small cell lung cancer (Combination therapy, Late-stage disease) presented at the 42nd European Society for Medical Oncology Congress (ESMO-2017)
  • 05 Sep 2017 ARMO BioSciences initiates a phase I pharmacokinetics trial in healthy volunteers in USA (NCT03267732)
  • 29 Aug 2017 ARMO Biosciences plans a phase I pharmacokinetics trial in Healthy volunteers (SC, injection) (NCT03267732)
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