Axicabtagene ciloleucel

Drug Profile

Axicabtagene ciloleucel

Alternative Names: KTE-C19; KTE-C19 CAR

Latest Information Update: 24 Jan 2017

Price : $50

At a glance

  • Originator Cabaret Biotech
  • Developer Genentech; Kite Pharma; National Cancer Institute (USA)
  • Class Antineoplastics; CAR-T cell therapies
  • Mechanism of Action CD19 antigen modulators; Gene transference; T lymphocyte replacements; T-cell receptor antigen modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Diffuse large B cell lymphoma; Chronic lymphocytic leukaemia; Mantle-cell lymphoma; Acute lymphoblastic leukaemia; Follicular lymphoma
  • New Molecular Entity No

Highest Development Phases

  • Preregistration Non-Hodgkin's lymphoma
  • Phase II Mantle-cell lymphoma
  • Phase I/II Acute lymphoblastic leukaemia
  • Phase I Leukaemia

Most Recent Events

  • 10 Jan 2017 Axicatagene ciloleucel sub-licensed to Daiichi Sankyo in Japan
  • 10 Jan 2017 Axicatagene ciloleucel licensed to Kite Pharma - Fosun Pharma (JV) in China
  • 10 Jan 2017 Preclinical trials in Leukaemia in China (Parenteral)
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