PLX 8394

Drug Profile

PLX 8394

Alternative Names: PLX-8394

Latest Information Update: 05 Oct 2016

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At a glance

  • Originator Plexxikon
  • Class Antineoplastics
  • Mechanism of Action Proto oncogene protein b raf inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Hairy cell leukaemia; Malignant melanoma; Solid tumours

Most Recent Events

  • 05 Oct 2016 Phase-I/II development is ongoing in USA
  • 01 Apr 2015 Plexxikon initiates a phase I/II trial in Solid tumours (Late-stage disease) in USA (PO) (NCT02428712)
  • 15 Sep 2014 Plexxikon terminates a phase I/II trial in Malignant melanoma (late-stage disease), Hairy cell leukaemia (late-stage disease) and Solid tumours (late-stage disease) in USA (NCT02012231)
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