RG 6125

Drug Profile

RG 6125

Alternative Names: RG6125; SDP-051

Latest Information Update: 30 May 2017

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At a glance

  • Originator Adheron Therapeutics
  • Developer Adheron Therapeutics; Roche
  • Class Antifibrotics; Antirheumatics; Monoclonal antibodies
  • Mechanism of Action Osteoblast cadherin inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Rheumatoid arthritis
  • Preclinical Cancer; Non-alcoholic steatohepatitis
  • No development reported Fibrosis

Most Recent Events

  • 16 May 2016 No development reported - Phase-I for Fibrosis (In volunteers) in USA (Parenteral)
  • 24 Nov 2015 Adheron plans a phase II trial for Rheumatoid arthritis in USA
  • 09 Oct 2015 Roche acquires SDP 051 from Adheron Therapeutics
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