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Research programme: TGF-beta antisense oligonucleotides - Isarna Therapeutics

Drug Profile

Research programme: TGF-beta antisense oligonucleotides - Isarna Therapeutics

Alternative Names: ASPH-0047; ASPH-1047; ASPH-1106; ISTH0047

Latest Information Update: 16 May 2023

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At a glance

  • Originator Isarna Therapeutics
  • Class Antifibrotics; Antiglaucomas; Antineoplastics; Antisense oligonucleotides; Hepatoprotectants
  • Mechanism of Action Left right-determination factor inhibitors; Transforming growth factor beta1 inhibitors; Transforming growth factor beta2 inhibitors; Transforming growth factor beta3 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Cancer; Fibrosis; Glaucoma; Non-alcoholic steatohepatitis

Most Recent Events

  • 16 May 2023 Preclinical trials in Non-alcoholic steatohepatitis in Germany, prior to May 2023 (Parenteral) (Isarna Therapeutics pipeline, May 2023)
  • 27 Mar 2023 Research programme is still in preclinical studies for Cancer, Glaucoma and Fibrosis in Germany (Isarna therapeutics pipeline, March 2023)
  • 28 Feb 2019 No recent reports of development identified for preclinical development in Cancer in Germany (Parenteral)
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