Drug Profile


Alternative Names: Anti-CD19 monoclonal antibody - Merck KGaA; DI-B4

Latest Information Update: 17 Jan 2014

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At a glance

  • Originator Merck KGaA
  • Developer Cancer Research Technology; Cancer Research UK
  • Class Antineoplastics; Monoclonal antibodies
  • Mechanism of Action CD19 antigen inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase I B cell lymphoma; Chronic lymphocytic leukaemia

Most Recent Events

  • 24 Jul 2013 Phase-I clinical trials in B-cell lymphoma and Chronic lymphocytic leukaemia (late-stage disease, second-line therapy or greater) in United Kingdom (IV)
  • 04 Jan 2010 Preclinical trials in B-cell lymphoma in United Kingdom (IV)
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