Zirconium silicate

Drug Profile

Zirconium silicate

Alternative Names: Lokelma; Sodium zirconium cyclosilicate; UXSi-9; Ziconite; Zircon; ZS; ZS 9

Latest Information Update: 20 May 2017

Price : $50

At a glance

  • Originator ZS Pharma
  • Class Heavy metals; Minerals; Silicates; Transition elements
  • Mechanism of Action Potassium binding modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Preregistration Hyperkalaemia

Most Recent Events

  • 28 Apr 2017 AstraZeneca plans a phase II/III trial for Hyperkalaemia in Japan (PO, Suspension) (NCT03127644)
  • 17 Mar 2017 ZS Pharma receives complete response letter from the FDA for zirconium silicate in Hyperkalaemia
  • 03 Mar 2017 Phase-III clinical trials in Hyperkalaemia in Russia, South Korea (PO, Suspension) (NCT02875834)
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