Zirconium silicate

Drug Profile

Zirconium silicate

Alternative Names: Lokelma; Sodium zirconium cyclosilicate; UXSi-9; Ziconite; Zircon; ZS; ZS 9

Latest Information Update: 10 Sep 2017

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At a glance

  • Originator ZS Pharma
  • Class Heavy metals; Minerals; Silicates; Transition elements
  • Mechanism of Action Potassium binding modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Preregistration Hyperkalaemia

Most Recent Events

  • 17 Nov 2017 AstraZeneca plans the phase II ENERGIZE trial for Hyperkalaemia (Adjunctive therapy) in January 2018 (NCT03337477)
  • 09 Oct 2017 AstraZeneca plans a phase III trial for Hyperkalaemia in USA and Russia (NCT03303521)
  • 18 Sep 2017 AstraZeneca plans a phase I trial for Hyperkalaemia (In volunteers) in Hong Kong (PO) in October 2017 (NCT03283267)
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