Sulforafan alfadex

Drug Profile

Sulforafan alfadex

Alternative Names: SFX-01; Stabilised sulforaphane; Sulforadex; Sulforafan-alpha-cyclodextrin; Sulforaphane-alpha-cyclodextrin; Sulphoraphane-alfadex

Latest Information Update: 24 Nov 2016

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At a glance

  • Originator Evgen Pharma; Lalilab; PharmAgra Labs
  • Developer Evgen Pharma
  • Class Antineoplastics; Chemopreventatives; Phytotherapies
  • Mechanism of Action Androgen receptor antagonists; Hedgehog protein modulators; Histone deacetylase inhibitors; NF E2 related factor 2 stimulants; Signal transduction pathway modulators; Wnt signalling pathway modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Phase II Breast cancer; Subarachnoid haemorrhage
  • Preclinical Cardiovascular disorders; Chronic obstructive pulmonary disease; Leukaemia; Multiple sclerosis

Most Recent Events

  • 01 Oct 2016 Phase-II clinical trials in Breast cancer (Second-line therapy or greater, Combination therapy, Metastatic disease, Late-stage disease) in Belgium (PO) (NCT02970682)
  • 14 Sep 2016 Preclinical trials in Multiple sclerosis in United Kingdom (PO)
  • 14 Sep 2016 Pharmacodynamics data from a preclinical study in Multiple sclerosis presented at the 32nd Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRMS-2016)
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