AMP 514

Drug Profile

AMP 514

Alternative Names: AMP-514; MEDI-0680

Latest Information Update: 17 Oct 2017

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At a glance

  • Originator Amplimmune
  • Developer Amplimmune; MedImmune
  • Class Antineoplastics; Monoclonal antibodies
  • Mechanism of Action PDCD 1 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II B cell lymphoma
  • Phase I Solid tumours

Most Recent Events

  • 18 May 2017 MedImmune completes a phase I trial for Solid tumours in USA (NCT02013804)
  • 01 Apr 2017 Pharmacodynamics and pharmacokinetics data from a phase I trial in Solid tumours presented at the 108th Annual Meeting of the American Association for Cancer Research
  • 07 Oct 2016 Efficacy, adverse event and immunogenicity data from a phase I trial in Cancer presented at the 41st European Society for Medical Oncology Congress (ESMO-2016)
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