Drug Profile


Alternative Names: ALN AT3; ALN-AT3SC; SAR 439774

Latest Information Update: 12 Jul 2017

Price : $50

At a glance

  • Originator Alnylam Pharmaceuticals
  • Developer Alnylam Pharmaceuticals; Sanofi Genzyme
  • Class Antifibrinolytics; Antihaemorrhagics; Antisense RNA; Drug conjugates; Small interfering RNA
  • Mechanism of Action Antithrombin III inhibitors; Haemostasis stimulants; RNA interference
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Haemophilia A; Haemophilia B
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Haemophilia A; Haemophilia B

Most Recent Events

  • 10 Jul 2017 Positive efficacy and adverse events data from an open label extension phase II trial in Haemophilia A and Haemophilia B released by Alnylam and Sanofi Genzyme
  • 07 Jul 2017 Phase-III clinical trials in Haemophilia A and Haemophilia B (SC)
  • 07 Jul 2017 Alnylam and Sanofi initiate enrolment in the phase III ATLAS-PPX trial for Haemophilia A and Haemophilia B (Prevention) (SC)
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