PFK 158

Drug Profile

PFK 158

Alternative Names: ACT-PFK-158; PFK158

Latest Information Update: 13 Apr 2016

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At a glance

  • Originator University of Louisville
  • Developer Advanced Cancer Therapeutics
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Glucose modulators; PFKFB3 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Solid tumours

Most Recent Events

  • 01 Mar 2014 Phase-I clinical trials in Solid tumours in USA (IV) (NCT02044861)
  • 22 Jan 2014 Preclinical trials in Solid tumours in USA (IV)
  • 22 Jan 2014 Advanced Cancer Therapeutics plans a phase I trial for Solid tumours (second-line therapy or greater, late-stage disease) in USA (NCT02044861)
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