Dendritic cell vaccine - Medigene

Drug Profile

Dendritic cell vaccine - Medigene

Alternative Names: DC vaccine - Medigene Immunotherapies; IL-12p70 DC vaccine; Leukemia-associated RNA transfected autologous dendritic cell vaccine - Medigene Immunotherapies; PRAME-mRNA-transfected dendritic cell vaccines - Medigene Immunotherapies; TLR-7/8-polarised dendritic cell vaccines - Medigene Immunotherapies; WT1-mRNA-transfected dendritic cell vaccines - Medigene Immunotherapies

Latest Information Update: 11 Apr 2017

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At a glance

  • Originator Trianta Immunotherapies
  • Developer Ludwig-Maximilians-University; Medigene Immunotherapies; University of Oslo
  • Class Cancer vaccines; Dendritic cell vaccines
  • Mechanism of Action Immunostimulants; Natural killer cell stimulants; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Phase II Acute myeloid leukaemia; Prostate cancer

Most Recent Events

  • 04 Apr 2017 Efficacy data from a compassionate-use study in Acute myeloid leukaemia presented at the 108th Annual Meeting of the American Association for Cancer Research (AACR-2017)
  • 31 Mar 2017 Ludwig-Maximilians - University of Munich suspends a phase I/II trial in Acute myeloid leukaemia (Second-line therapy or greater) in Germany (Intradermal) (NCT01734304)
  • 03 Dec 2016 Immunogenicity and adverse event data from a phase I/II trial in Acute myeloid leukaemia presented at the 58th Annual Meeting and Exposition of the American Society of Haematology (ASH-2016)
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