PU H71

Drug Profile

PU H71

Alternative Names: PU-H71; Purine-scaffold HSP90 inhibitor - Samus

Latest Information Update: 27 Apr 2017

Price : $50

At a glance

  • Originator Memorial Sloan-Kettering Cancer Center
  • Developer Memorial Sloan-Kettering Cancer Center; National Cancer Institute (USA); Samus Therapeutics
  • Class Antineoplastics; Purines; Small molecules
  • Mechanism of Action HSP90 heat-shock protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Myelofibrosis
  • Phase I Breast cancer; Lymphoma; Non-Hodgkin's lymphoma; Pancreatic cancer; Solid tumours

Most Recent Events

  • 30 Mar 2017 Samus Therapeutics plans a phase Ib trial for Breast cancer (Combination therapy, First-line therapy, Metastatic disease)
  • 30 Mar 2017 Phase-I clinical trials in Breast cancer (Late-stage disease, Combination therapy) in USA (IV)
  • 30 Mar 2017 Phase-I clinical trials in Pancreatic cancer (Combination therapy, First-line therapy, Metastatic disease) in USA (IV)
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