PXS 4728A

Drug Profile

PXS 4728A

Alternative Names: PXS4728; PXS4728A; Semicarbazide‐sensitive amine oxidase/vascular adhesion protein‐1 inhibitor - Pharmaxis; SSAO/VAP‐1 inhibitor - Pharmaxis

Latest Information Update: 22 Sep 2015

Price : $50

At a glance

  • Originator Pharmaxis
  • Developer Pharmaxis; University of Sydney
  • Class Anti-inflammatories; Small molecules
  • Mechanism of Action AOC3 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Chronic obstructive pulmonary disease; Cystic fibrosis
  • Preclinical Asthma; Non-alcoholic steatohepatitis; Renal fibrosis

Most Recent Events

  • 15 May 2017 Boehringer Ingelheim plans a phase II trial for Non-alcoholic steatohepatitis by mid-year 2017
  • 15 May 2017 Boehringer Ingelheim plans a phase II trial in an undisclosed indication in 2017
  • 21 Sep 2015 Efficacy and adverse events data from a phase I trial in Chronic obstructive pulmonary disease and Cystic fibrosis (In volunteers) released by Pharmaxis
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