Research programme: mannose receptor-targeted diagnostic and therapeutic agents - Macrophage Therapeutics

Drug Profile

Research programme: mannose receptor-targeted diagnostic and therapeutic agents - Macrophage Therapeutics

Alternative Names: CD206 receptor-targeted diagnostics - Navidea Biopharmaceuticals; Cy3-Manocept; Cy3-Manocept-doxorubicin; Cy3-tilmanocept; Manocept™-derived diagnostic agents - Navidea Biopharmaceuticals; MT 1000; MT 1001; MT 2000; MT 2001; MT 2002

Latest Information Update: 31 May 2016

Price : $50

At a glance

  • Originator Navidea Biopharmaceuticals
  • Developer Macrophage Therapeutics; Navidea Biopharmaceuticals; University of California at San Francisco
  • Class Diagnostic agents; Small molecules
  • Mechanism of Action Diagnostic imaging enhancers; Mannose receptor modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • On Fast track

    Fast track status is assigned by the US FDA so therapies with the potential to address unmet needs can move faster through development.

  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Autoimmune disorders; Cancer; Cardiovascular disorders; CNS disorders; Infections; Kaposi's sarcoma; Non-alcoholic fatty liver disease; Rheumatoid arthritis; Tuberculosis

Most Recent Events

  • 26 May 2016 Navidea Biopharmaceuticals receives SBIR grant from National Institutes of Health’s (NIH) National Cancer Institute (NCI) for Manocept™-based immunotargeted treatment in Kaposi’s Sarcoma
  • 26 May 2016 Navidea Biopharmaceuticals plans to file an IND application with the US FDA for phase I/II clinical trial in Kaposi's sarcoma
  • 17 May 2016 Preclinical trials in Non-alcoholic fatty liver disease in USA (unspecified route)
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