Drug Profile


Alternative Names: JNJ-42847922; MIN-202

Latest Information Update: 29 Sep 2017

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At a glance

  • Originator Janssen Research & Development
  • Developer Janssen Research & Development; Minerva Neurosciences
  • Class Antidepressants; Sleep disorder therapies
  • Mechanism of Action Orexin receptor type 2 antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Insomnia; Major depressive disorder

Most Recent Events

  • 01 Sep 2017 Phase-II clinical trials in Major depressive disorder (Adjunctive treatment) in USA (PO)
  • 25 Aug 2017 European Commission approves amendment to co-development and license agreement between Minerva Neurosciences and Janssen
  • 22 Aug 2017 Janssen plans a phase I trial in Healthy volunteers in Belgium (NCT03249402)
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