Drug Profile


Alternative Names: MK-8408

Latest Information Update: 06 Jan 2017

Price : $50

At a glance

  • Originator Merck Sharp & Dohme
  • Class Antivirals; Benzoxazines; Carbamates; Cyclopropanes; Esters; Imidazoles; Pyrrolidines; Thiazoles
  • Mechanism of Action Hepatitis C virus NS 5 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Hepatitis C

Most Recent Events

  • 01 Dec 2016 Merck completes a phase-II trial in Hepatitis C (Combination therapy, Treatment-naive) in Australia, Austria, Canada, Denmark, France, Germany, Israel, Italy, Lithuania, New Zealand, Poland, Puerto Rico, Spain, Sweden, United Kingdom and USA (PO) (NCT02332707; EudraCT2014-003304-73)
  • 01 Nov 2016 Merck initiates a phase II trial for Hepatitis C (Combination therapy, Treatment-naïve, Treatment-experienced) in USA (NCT02956629)
  • 01 May 2016 Phase-II clinical trials in Hepatitis C (Combination therapy, Treatment-naïve, Treatment-experienced) in USA (PO) (NCT02759315)
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