Drug Profile


Alternative Names: aTyr 1920; HisRSN4 - aTyr Pharma; Histidyl-tRNA synthetase - aTyr Pharma; HRS (1-60) - aTyr Pharma; Resected-tRNA synthetase - aTyr Pharma; Resokine IV; Truncated-tRNA synthetase - aTyr Pharma

Latest Information Update: 08 Mar 2016

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At a glance

  • Originator aTyr Pharma
  • Class Amino acids peptides and proteins; Amino acyl-tRNA synthetases; Aminoacyltransferases; Biological proteins; Proteins
  • Mechanism of Action Histidine-tRNA ligase modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • No development reported Immunological disorders; Inflammatory bowel diseases

Most Recent Events

  • 21 May 2014 Adverse events data from a phase I trial in Immunological disorders released by aTyr
  • 21 May 2014 aTyr completes a phase I trial in Immunological disorders in European Union
  • 24 Feb 2014 Phase-I clinical trials in Immunological disorders (in volunteers) in European Union (IV)
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