Either you have JavaScript disabled or your browser does not support Javascript . To work properly, this page requires JavaScript to be enabled.
How to enable JavaScript in your browser?

Esreboxetine - Axsome Therapeutics

Next Previous
Drug Profile

Esreboxetine - Axsome Therapeutics

Alternative Names: [S,S]-Reboxetine; AXS-14; PNU-165442G

Latest Information Update: 23 Jan 2026

Price :
$50 *
Note:
  • Adis is an information provider. We do not sell or distribute actual drugs.
  • Final gross price and currency may vary according to local VAT and billing address.
  • Your purchase entitles you to full access to the information contained in our drug profile at the time of purchase.
  • A link to download a PDF version of the drug profile will be included in your email receipt.

At a glance

  • Originator Pfizer
  • Developer Axsome Therapeutics; Pfizer
  • Class Antidepressants; Morpholines; Small molecules; Urologics
  • Mechanism of Action Adrenergic uptake inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preregistration Fibromyalgia
  • Discontinued Diabetic neuropathies; Major depressive disorder; Postherpetic neuralgia; Urinary-Stress-Incontinence

Most Recent Events

  • 15 Jan 2026 Axsome Therapeutics initiates the phase III FORWARD trial in Fibromyalgia in USA (PO)
  • 04 Aug 2025 Axsome Therapeutics plans a phase III trial for Fibromyalgia in USA in fourth quarter of 2025 (PO)
  • 09 Jun 2025 Axsome Therapeutics receives Refusal to File letter from the US FDA for Esreboxetine in Fibromyalgia

You need to be a logged in or subscribed to view this content

Request demo (opens in a new window)
If your organization or you do not have a subscription, try one of the following: If your organization has a subscription, there are several access options, even while working remotely:
  • Working within your organization’s network
  • with username/password or try to via your institution
  • Persisted access using your organization’s identifier stored in your user browser for 90 days
Back to top