DS 8273

Drug Profile

DS 8273

Alternative Names: Anti-DR5 monoclonal antibody - Daiichi Sankyo; DS-8273a; DS8273

Latest Information Update: 16 Dec 2016

Price : $50

At a glance

  • Originator Daiichi Sankyo Inc
  • Developer Bristol-Myers Squibb; Daiichi Sankyo Inc; New York University School of Medicine
  • Class Antineoplastics; Monoclonal antibodies
  • Mechanism of Action Apoptosis stimulants; Immunomodulators; TRAIL receptor 2 agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Colorectal cancer; Lymphoma; Malignant melanoma; Solid tumours

Most Recent Events

  • 01 Dec 2016 Phase-I clinical trials in Colorectal cancer (Metastatic disease, Inoperable/Unresectable, Second-line therapy or greater, Late-stage disease, Combination therapy) in USA (IV) (NCT02991196)
  • 01 Oct 2016 Phase-I clinical trials in Malignant melanoma (Combination therapy, Late-stage disease, Second-line therapy or greater, Inoperable/Unresectable, Metastatic disease) in USA (IV) (NCT02983006)
  • 01 Dec 2015 Daiichi Sankyo completes a phase I trial in Solid tumours and Lymphoma (Late stage disease) in USA (IV) (NCT02076451)
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