Drug Profile


Alternative Names: Ferroquine/artefenomel; Ferroquine/OZ439; OZ439 mesylate/ferroquine; OZ439/4-aminoquinoline

Latest Information Update: 10 Sep 2017

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At a glance

  • Originator Medicines for Malaria Venture
  • Developer Medicines for Malaria Venture; Sanofi
  • Class Adamantanes; Aminoquinolines; Antimalarials; Cyclohexanes; Ferrous compounds; Morpholines; Peroxides; Small molecules
  • Mechanism of Action Hemozoin inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Falciparum malaria; Malaria

Most Recent Events

  • 17 Jul 2015 Sanofi plans a phase IIb trial for Falciparum malaria in Gabon (NCT02497612)
  • 01 Jul 2015 Phase-II clinical trials in Falciparum malaria (In adults, In children, In infants, In adolescents, In the elderly) in Gabon (PO) (NCT02497612)
  • 06 Feb 2014 Phase-II clinical trials in Malaria treatment in USA (PO)
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