CFZ 533

Drug Profile

CFZ 533

Alternative Names: CFZ533; OM11-62-MF

Latest Information Update: 13 Jun 2017

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At a glance

  • Originator Novartis
  • Class Antirheumatics; Monoclonal antibodies
  • Mechanism of Action CD40 antigen inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Graves' disease; Myasthenia gravis; Sjogren's syndrome
  • Phase I/II Renal transplant rejection
  • Phase I Rheumatoid arthritis

Most Recent Events

  • 24 Apr 2017 Novartis completes a phase-II trial in Graves' disease in USA, Germany (NCT02713256)
  • 21 Mar 2017 Novartis Pharmaceuticals completes a phase I trial in Rheumatoid arthritis in USA and Taiwan (NCT02089087)
  • 11 Nov 2016 Phase I development is ongoing for Rheumatoid arthritis in USA (IV, SC)
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