Acidified nitrite - Arch Biopartners/University of Cincinnati

Drug Profile

Acidified nitrite - Arch Biopartners/University of Cincinnati

Alternative Names: A-NO2 - Arch Biopartners/University of Cincinnati; AB 569; ABP-569

Latest Information Update: 05 Oct 2017

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At a glance

  • Originator University of Cincinnati
  • Class Anions; Antibacterials; Antihypertensives; Nitrites; Nitrogen compounds; Organic chemicals; Vasodilators
  • Mechanism of Action Bacterial growth inhibitors; Nitric oxide stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Pseudomonal infections
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Pseudomonal infections
  • Preclinical Burkholderia cepacia infections; Staphylococcal infections

Most Recent Events

  • 28 Sep 2017 Arch Biopartners plans a phase I safety trial in Healthy volunteers (Inhalation) at the end of 2017 or in January 2018
  • 28 Sep 2017 Arch Biopartners, Cincinnati Veterans Affairs Medical Center and University of Cincinnati College of Medicine plans a phase II trial in Pseudomonal infections (Inhalation)
  • 15 Dec 2016 Biomarkers information updated
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