WT1 TCR-transduced T-cell therapy - Takara Bio

Drug Profile

WT1 TCR-transduced T-cell therapy - Takara Bio

Alternative Names: WT1 antigen-specific RetroNectin TCR gene therapy - Takara Bio; WT1 antigen-specific TCR-gene-transduced autologous lymphocytes - Takara Bio

Latest Information Update: 03 Feb 2017

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At a glance

  • Originator Takara Bio
  • Developer Mie University; Takara Bio
  • Class T lymphocyte cell therapies
  • Mechanism of Action Gene transference; Immunostimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Phase I Acute myeloid leukaemia; Myelodysplastic syndromes

Most Recent Events

  • 03 Dec 2016 Efficacy and safety data from a phase I trial in acute myeloid leukaemia and myelodysplastic syndrome presented at the 58th Annual Meeting and Exposition of the American Society of Hematology (ASH-2016)
  • 05 Nov 2016 Mie University terminates phase I trial in Acute myeloid leukaemia and Myelodysplastic syndrome in Japan (UMIN000017431)
  • 01 Nov 2016 Takara Bio completes a phase I trial in Acute Myeloid leukaemia and myelodysplastic syndromes (second line therapy or greater) in Japan (SC) (UMIN000011519)
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