Research programme: antibacterials - Spero Therapeutics/Roche

Drug Profile

Research programme: antibacterials - Spero Therapeutics/Roche

Alternative Names: Multiple virulence factor Regulator inhibitors - Spero; MvfR inhibitors - Spero; MvfR programme - Spero

Latest Information Update: 12 Jul 2017

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At a glance

  • Originator Spero Therapeutics
  • Class Antibacterials; Small molecules
  • Mechanism of Action Transcription factor inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Gram-negative infections; Pseudomonal infections

Most Recent Events

  • 25 Apr 2017 Pharmacodynamic results from a preclinical study in Pseudomonal infections presented at the 27th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID-2017)
  • 15 Dec 2015 Spero Therapeutics and Evotec AG agree to co-develop antibacterials for Gram-negative infections
  • 25 Aug 2014 Antimicrobial activity data from preclinical studies in Pseudomonal infections released by Spero Therapeutics
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