AG 348

Drug Profile

AG 348

Alternative Names: AG348

Latest Information Update: 05 Sep 2017

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At a glance

  • Originator Agios Pharmaceuticals
  • Class Antianaemics; Small molecules
  • Mechanism of Action Pyruvate kinase stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Inborn error metabolic disorders
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Haemolytic anaemia

Most Recent Events

  • 09 Aug 2017 Agios Pharmaceutical initiates enrolment in a phase I trial in Healthy volunteers in USA (NCT03250598)
  • 27 Jun 2017 Updated safety and efficacy data from phase II DRIVE-PK trial in Haemolytic anaemia (associated with pyruvate kinase deficiency) were presented at the 22nd Congress of the European Haematology Association (EHA-2017)
  • 25 Jun 2017 Adverse events data from the phase II DRIVE-PK trial in Haemolytic anaemia presented at the 22nd Congress of the European Haematology Association (EHA-2017)
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