Drug Profile


Alternative Names: Epclusa; Fixed-dose combination of sofosbuvir and GS-5816 - Gilead Sciences; GS 5816/sofosbuvir; GS 7977/GS 5816; SOF/GS-5816; SOF/VEL; Sofosbuvir/GS 5816; Velpatasvir/sofosbuvir

Latest Information Update: 14 Feb 2017

Price : $50

At a glance

  • Originator Gilead Sciences
  • Class Antivirals; Carbamates; Chromans; Imidazoles; Naphthols; Phenylacetates; Phosphoric acid esters; Pyrimidine nucleotides; Pyrrolidines; Small molecules
  • Mechanism of Action Hepatitis C virus NS 5 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Hepatitis C

Most Recent Events

  • 27 Jan 2017 Gilead Sciences plans the phase II SOF/VEL ESRD trial for Hepatitis C (NCT03036852)
  • 01 Jan 2017 Gilead Sciences completes a phase III trial in Hepatitis C (Treatment-experienced) in USA, Australia, Canada, France, Germany, New Zealand, Puerto Rico, United Kingdom (PO) (NCT02639247) (EudraCT2015-003167-10)
  • 01 Jan 2017 Gilead Sciences completes a phase III trial for Hepatitis-C in Australia, Canada, France, Germany, Puerto Rico and United Kingdom, USA and New Zealand (NCT02639338)
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