Research programme: small-molecule oral therapeutics - Principia Biopharma

Drug Profile

Research programme: small-molecule oral therapeutics - Principia Biopharma

Alternative Names: PRN 2246

Latest Information Update: 28 Jan 2017

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At a glance

  • Originator Principia Biopharma
  • Class Small molecules
  • Mechanism of Action Agammaglobulinaemia tyrosine kinase inhibitors; Interleukin 17 receptor antagonists; Interleukin-17 inhibitors; Proteasome inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Autoimmune disorders; CNS disorders; Inflammation
  • Discontinued Haematological malignancies

Most Recent Events

  • 18 Oct 2017 Principia Biopharma plans a phase I trial for Multiple sclerosis (In Volunteers) in Australia in April 2018 (ACTRN12617001457336)
  • 27 Jan 2017 Discontinued - Preclinical for Haematological malignancies in USA (PO)
  • 27 Jan 2017 Preclinical trials in Autoimmune disorders in USA (PO)
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